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Fluoroquinolone Antibiotic Resistance Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic markers that may indicate resistance to fluoroquinolone antibiotics, commonly used to treat bacterial infections.

Quick summary

["Helps determine if a bacterial infection might not respond to fluoroquinolone antibiotics as expected."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74040-7
Short code
FLUAV N2 RNA Ct Spec Qn NAA+probe
Synonyms
FLUAV N2 RNA Ct Spec Qn NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a suspected bacterial infection that doesn’t improve with fluoroquinolone treatment, or if you’re considering this antibiotic for a specific infection. It’s also used in research or clinical settings to monitor antibiotic resistance trends.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The sample is collected in a tube that separates serum or plasma from blood cells.

What the Test Measures

This test detects specific genetic sequences (probes) in your blood that could signal bacteria resistant to fluoroquinolone antibiotics. It’s not a direct measurement of antibiotic levels in your body but rather an indirect check for resistance mechanisms.

What the Results Mean

Results are qualitative (positive or negative) and indicate whether the genetic markers for fluoroquinolone resistance are present. Positive results suggest potential resistance, but further testing or clinical correlation is needed to guide treatment decisions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fluoroquinolone Resistance Screening

Frequently asked questions

Your healthcare provider will use these results alongside clinical findings, culture results, and patient history to decide if alternative antibiotics are needed. Resistance patterns help guide treatment plans to prevent the spread of antibiotic-resistant bacteria.
This test is primarily used in research or specialized clinical settings to assess antibiotic resistance in bacterial infections. It’s not a routine diagnostic tool for most patients.
What does a positive result mean?
A positive result suggests that the bacteria in your sample may carry genetic markers linked to fluoroquinolone resistance. This doesn’t confirm the infection is resistant; it’s a preliminary indicator that further testing or alternative treatments may be needed.
Does this test replace culture and sensitivity testing?
No, this test is a screening tool. Culture and sensitivity testing remains the gold standard for confirming bacterial infections and identifying the most effective antibiotic treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy