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Fluoroquinolone (Antibiotic) Concentration in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fluoroquinolone antibiotics (a class of medications used to treat bacterial infections) in your blood. It helps doctors determine if the drug is working at the right level and adjust your treatment if needed.

Quick summary

["This test helps ensure your antibiotic is effective and safe at the right dose."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
39318-1
Short code
FLUAV N8 NAb Ser Ql Nt
Synonyms
FLUAV N8 NAb Ser Ql Nt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
neut
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you’re taking fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin) to check if the medication is reaching the right concentration in your blood. It’s especially important for infections that require long-term treatment or when higher doses are needed. Your doctor may also use it to monitor for potential side effects or adjust your dose if needed.

What to Expect Before the Test

No special preparation is usually needed. You may have a small needle inserted into a vein (venipuncture) in your arm to draw blood. If you’re on this medication, your doctor will discuss how it may affect your results or timing of the test.

How the Test Works

Blood is collected and analyzed using a sensitive method (likely immunoassay or chromatography) to measure the exact amount of fluoroquinolone in your serum or plasma. This helps your doctor track how your body is processing the drug.

What the Results Mean

Results show the concentration of fluoroquinolone in your blood. Your doctor will compare these results to your treatment plan to decide if your dose should stay the same, be increased, or adjusted. They’ll also consider your symptoms and overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fluoroquinolone Level

Frequently asked questions

How often should fluoroquinolone levels be checked?
This depends on your specific medication, infection type, and doctor’s instructions. Some patients may need levels checked weekly during treatment, while others may only need it once or twice if their dose is stable.
Can food or other medications affect fluoroquinolone test results?
Generally, food doesn’t interfere with the test itself, but it may affect how the drug is absorbed in your body. Always tell your doctor about all medications (including vitamins or supplements) you’re taking, as some can influence fluoroquinolone levels.
What are the most common side effects of fluoroquinolone antibiotics?
Common side effects include nausea, diarrhea, or tendon pain. Rare but serious side effects (like allergic reactions or nerve damage) require immediate medical attention. Your doctor will weigh these risks against the benefits of treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy