Fluoroquinolone Antibiotic Resistance Gene Detection in Nasopharyngeal Secretions by Sequencing
This test checks for specific genes linked to antibiotic resistance in bacteria found in your nose and throat. It helps determine if certain bacteria may not respond to fluoroquinolone antibiotics.
["This test helps guide treatment choices by identifying antibiotic-resistant bacteria."]
Key facts at a glance
- LOINC
- 87716-7
- Short code
- FLUAV NA gene Islt-Seq
- Synonyms
- FLUAV NA gene Islt-Seq
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- sequencing
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test analyzes genetic material (DNA) from bacteria present in your nasopharyngeal secretions. It specifically looks for genes that confer resistance to fluoroquinolone antibiotics, which are a class of broad-spectrum antibiotics used to treat infections like pneumonia, urinary tract infections, and certain skin infections. This genetic analysis is performed using next-generation sequencing technology, which can identify multiple genes at once.
Why It’s Done
Your healthcare provider may order this test if you have symptoms of an infection that could be caused by bacteria resistant to fluoroquinolones, or if you’ve been prescribed these antibiotics and the infection isn’t improving. It’s also used in certain clinical settings to monitor resistance patterns in bacterial populations.
Sample Collection and Preparation
A healthcare professional will collect a sample from your nose and throat using a swab. The swab is then processed to extract DNA from any bacteria present. This genetic material is then sequenced to identify antibiotic resistance genes.
How Results Are Interpreted
Results are typically reported as the presence or absence of specific resistance genes. If resistance genes are detected, it means certain bacteria in your sample may not respond to fluoroquinolone antibiotics. Your healthcare provider will use these results to adjust your treatment plan.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Identifying fluoroquinolone-resistant bacteria is crucial for effective infection management. Fluoroquinolones are important antibiotics, but overuse or misuse can lead to resistance. Detecting resistance helps prevent unnecessary antibiotic use, reduces the risk of treatment failure, and supports the responsible use of antibiotics to preserve their effectiveness for future infections.
Short name
NA
Frequently asked questions
What does a positive result mean?
How long does it take to get results?
Can I take antibiotics before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy