Skip to content

Fluoroquinolone Antibiotic Resistance Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of certain genetic markers that may indicate resistance to fluoroquinolone antibiotics, which are commonly used to treat bacterial infections.

Quick summary

["Helps determine if a bacterial infection might not respond to fluoroquinolone antibiotics."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
55134-1
Short code
FLUAV NA RNA Islt NAA+probe
Synonyms
FLUAV NA RNA Islt NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a bacterial infection that doesn’t improve with fluoroquinolone treatment, or if you’re considering this type of antibiotic for a specific infection. It can also be used in research or clinical settings to monitor antibiotic resistance patterns.

What to Expect Before the Test

No special preparation is typically needed. You may provide a blood sample, which is usually taken from a vein in your arm. If you’re unsure about timing, follow your healthcare provider’s instructions.

What the Test Measures

This test detects specific genetic sequences (probes) in your blood that are associated with fluoroquinolone resistance in bacteria. It’s not a direct measurement of antibiotic levels in your body but rather an indirect check for bacterial resistance.

How the Results Are Used

Results help guide antibiotic choices to ensure the right treatment is selected. If resistance is detected, your provider may adjust your treatment plan or choose a different antibiotic class.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fluoroquinolone Resistance Screen

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of genetic markers linked to fluoroquinolone resistance in bacteria present in your blood. This doesn’t confirm an active infection but may indicate the bacteria could be resistant to this class of antibiotics.
Will I need to take any antibiotics if this test is positive?
Not necessarily. A positive result means the bacteria may be resistant, but it doesn’t mean you’ll automatically start a different antibiotic. Your healthcare provider will review your clinical picture and decide on the best course of action, possibly including alternative treatments or supportive care.
Can this test be done on other specimens besides blood?
This specific test is primarily performed on serum or plasma samples. If your infection involves other body fluids (like urine or sputum), your provider may order a different test tailored to that specimen.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy