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Antibody to Flavivirus Nucleocapsid Protein (IgG)

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against the nucleocapsid protein of flaviviruses, which includes viruses like dengue, Zika, and West Nile. It helps determine if your immune system has been exposed to these viruses.

Quick summary

["This test helps diagnose past infection with flaviviruses, which can cause fever, rash, and neurological symptoms."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50708-7
Short code
FLUAV PB2 RNA Islt Ql Seq
Synonyms
FLUAV PB2 RNA Islt Ql Seq
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
sequencing
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

The test detects IgG antibodies specific to the nucleocapsid protein of flaviviruses. These antibodies develop in your blood after your immune system has encountered the virus. The presence of these antibodies suggests a previous infection, though they may persist long after symptoms have resolved.

Why Might I Need This Test?

Your healthcare provider may order this test if you have symptoms of a flavivirus infection (such as fever, headache, or rash) and suspect exposure to dengue, Zika, or West Nile virus. It can also be used in research or epidemiological studies to track virus spread.

Sample Collection and Preparation

A blood sample is typically drawn from a vein in your arm. The blood is processed to separate serum (liquid part of blood without clots), which is then tested for the antibodies.

What to Expect Before the Test

No special preparation is needed for this test. You may have some mild discomfort or bruising at the injection site, but this usually goes away quickly.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily used to confirm past infection with flaviviruses, which can help diagnose conditions like dengue fever, Zika virus disease, or West Nile virus infection. It can also be useful in identifying exposure in travelers, research participants, or individuals with unexplained symptoms. However, it cannot distinguish between different flaviviruses or confirm active infection.

Short name

IgG Antibody to Flavivirus Nucleocapsid

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will contact you with the results once they are ready.
Can this test detect active infection with flaviviruses?
No, this test only detects antibodies, which indicate a past infection. To diagnose an active infection, your provider may use other tests, such as viral RNA detection or antibody tests for acute infection.
What are the possible reasons for a positive result?
A positive result suggests you have been previously exposed to a flavivirus. This could be from infection, vaccination, or cross-reactivity with other related viruses. Always discuss your results with your healthcare provider for personalized interpretation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy