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Fluorescent Immunoassay for Anti-Nuclear Antibodies (ANA) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies your immune system may produce against proteins in your cell nucleus, which can help identify certain autoimmune conditions.

Quick summary

["ANA testing helps diagnose autoimmune diseases by detecting unusual antibodies in your blood."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
88193-8
Short code
FLUAV RNA Corn/Cnjt Ql NAA+probe
Synonyms
FLUAV RNA Corn/Cnjt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order an ANA test if you have symptoms like joint pain, fatigue, rash, or unexplained fever. It’s often used as a screening test for conditions like lupus, rheumatoid arthritis, or other autoimmune disorders.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from your arm. The test checks for antibodies in your serum, the liquid part of blood.

What the Test Results Mean

Results are not always definitive on their own. A positive ANA test increases suspicion for autoimmune diseases, but further testing is needed to confirm a diagnosis. Results are often reported as a titer level (e.g., 1:40, 1:160) to show antibody strength.

Common Conditions Linked to ANA

A positive ANA test can signal conditions like systemic lupus erythematosus (SLE), scleroderma, rheumatoid arthritis, or mixed connective tissue disease. However, not everyone with these conditions will test positive.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

ANA testing is a broad screening tool. While a positive result raises concern for autoimmune diseases, it doesn’t confirm a diagnosis alone. Follow-up tests, such as specific antibody panels or clinical correlation, are required for accurate diagnosis. False positives can occur, especially in early disease or certain infections.

Short name

ANA Fluorescence Probe

Frequently asked questions

What does an ANA test measure?
The ANA test detects antibodies your body produces against nuclear components in cells. These antibodies are linked to autoimmune diseases but can also appear in healthy individuals or those with infections.
How long does it take to get ANA test results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow-up with your healthcare provider is needed to discuss results and next steps.
Can lifestyle changes affect ANA test results?
No, ANA test results are based on your blood sample and don’t change with diet, exercise, or stress. However, certain medications (like steroids) or infections may influence antibody levels temporarily.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy