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Fluoroquinolone Antibiotic Resistance Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects the presence of genetic markers linked to antibiotic resistance in fluoroquinolone drugs, which are commonly used to treat bacterial infections.

Quick summary

["Helps determine if bacteria may be resistant to fluoroquinolone antibiotics before treatment begins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44263-2
Short code
FLUAV RNA Spec NAA+probe-aCnc
Synonyms
FLUAV RNA Spec NAA+probe-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test analyzes genetic material (DNA) from bacteria in your serum or plasma to check for specific mutations. These mutations can make bacteria resistant to fluoroquinolone antibiotics, which are used to treat infections like urinary tract infections, pneumonia, and certain types of skin infections. The probe detects these genetic changes to help guide treatment decisions.

Why It Might Be Ordered

Your healthcare provider may order this test if you have a bacterial infection that doesn’t respond well to fluoroquinolone antibiotics, or if you’re considering this type of treatment. It’s also used in research or clinical settings to monitor antibiotic resistance trends in bacteria.

How the Test Works

The test uses a molecular probe to identify genetic sequences associated with fluoroquinolone resistance. A small sample of your blood (serum or plasma) is collected and analyzed in a laboratory. The probe binds to specific DNA sequences if they’re present, indicating potential resistance.

Preparation for the Test

No special preparation is needed for this test. You may have a simple blood draw, similar to other routine blood tests. If you’re taking antibiotics, let your healthcare provider know before the test, as it may affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fluoroquinolone Resistance Test

Frequently asked questions

This test helps healthcare providers determine if bacteria causing your infection are resistant to fluoroquinolones. Early identification of resistance can lead to more effective treatment choices, reducing the risk of ineffective therapy or antibiotic resistance in the community.
This test is typically used in research or specialized clinical settings rather than routine patient care. It may not be covered by all insurance plans, so check with your provider about costs and coverage.
What does a positive result mean?
A positive result suggests the presence of genetic markers linked to fluoroquinolone resistance in the bacteria causing your infection. This does not confirm the bacteria are resistant; it only indicates a potential risk. Your healthcare provider will interpret results in the context of your clinical symptoms and other test results.
How long will it take to get results?
Results may take several days to a week, depending on the laboratory and whether this test is part of a larger research or clinical study. Your healthcare provider will contact you once results are available.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy