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Fluoroquinolone Antibiotic Resistance Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of genetic markers linked to antibiotic resistance in fluoroquinolone drugs, which are commonly used to treat bacterial infections.

Quick summary

["Helps determine if bacteria may become resistant to fluoroquinolones, guiding treatment decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108177-7
Short code
FLUAV RNA Spec Ql NAA+n-prb
Synonyms
FLUAV RNA Spec Ql NAA+n-prb
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

This test detects specific genetic sequences (probes) in your blood that indicate whether bacteria may develop resistance to fluoroquinolone antibiotics. Fluoroquinolones are a class of antibiotics used to treat infections like urinary tract infections, respiratory infections, and some sexually transmitted diseases.

Why It’s Done

Your healthcare provider may order this test if you’re prescribed fluoroquinolones, have a history of infections that may respond to these antibiotics, or if you’re at higher risk of antibiotic resistance. It helps ensure the most effective treatment by identifying potential resistance early.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is processed to separate serum or plasma for testing. This test is performed on the fluid portion of your blood, not whole blood.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re taking any medications, especially antibiotics, or if you have any allergies. Avoid eating or drinking anything (except water) for at least 8 hours before the test if instructed.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is primarily used in research or specialized clinical settings to assess antibiotic resistance patterns in bacterial infections. While it doesn’t replace standard culture tests, it can help guide treatment decisions in cases where resistance is suspected or documented in the bacteria causing your infection.

Short name

Fluoroquinolone Resistance Screening

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of genetic markers that may contribute to antibiotic resistance in fluoroquinolones. This doesn’t mean you have an infection now, but it indicates that bacteria in your body might become less responsive to these antibiotics over time if used repeatedly.
Will this test affect my treatment?
Possibly. If your infection is caused by bacteria that show resistance markers, your healthcare provider may choose a different antibiotic class or adjust your treatment plan to prevent resistance. Always follow your provider’s guidance based on this test result.
Can I still take fluoroquinolones if this test is positive?
Not necessarily. If your provider suspects resistance, they may recommend alternatives or monitor you closely. Fluoroquinolones are powerful antibiotics, and using them when resistance is likely can worsen outcomes. Always discuss this with your healthcare provider.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy