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Antibody to Flavivirus Nucleoprotein (IgG) - Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of antibodies against the nucleoprotein of flaviviruses, which include viruses like dengue, yellow fever, and Zika. It helps determine if your immune system has been exposed to these viruses.

Quick summary

["Checks for past exposure to flaviviruses through antibody detection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
107365-9
Short code
FLUAV RNA Spt Ql NAA+n-prb
Synonyms
FLUAV RNA Spt Ql NAA+n-prb
Category
chemistry
Sample
sputum
Container
Sterile sputum container
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
non-probe-amp-tar
CPT
85610
SNOMED
396252006
Specimen volume
3-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects IgG antibodies specific to the nucleoprotein of flaviviruses. These antibodies develop after your body has encountered the virus, typically several weeks to months after infection. This test is often used in research or specialized diagnostic settings rather than routine clinical practice.

Why It Might Be Ordered

Your healthcare provider may order this test if you have symptoms suggestive of flavivirus infection (e.g., fever, rash, joint pain) and live in or traveled to an area where these viruses are common. It can also be used in research studies or for specific diagnostic purposes in certain clinical scenarios.

How the Test Works

A blood sample is taken from you and sent to a laboratory. The serum is analyzed to detect IgG antibodies against flavivirus nucleoproteins using an immunoassay method. This method identifies the presence of these antibodies by detecting their interaction with a labeled probe.

Sample Collection and Preparation

A small amount of blood is drawn from a vein in your arm. The blood is then processed to separate the serum, which is the liquid part containing the antibodies. This serum is sent to the lab for testing.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: sputum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate past exposure to flaviviruses, suggesting your immune system has encountered these viruses. This can be useful in epidemiological studies, research, or for confirming exposure in specific clinical contexts. However, it does not indicate whether you currently have an active infection. Always consult your healthcare provider for interpretation of results in the context of your symptoms and medical history.

Short name

IgG Antibody to Flavivirus Nucleoprotein

Frequently asked questions

What does a positive result mean?
A positive result means your blood contains antibodies against flavivirus nucleoproteins, indicating your immune system has likely been exposed to one of these viruses in the past. This does not necessarily mean you had symptoms or an active infection at the time of testing.
What does a negative result mean?
A negative result means your blood does not have detectable antibodies against flavivirus nucleoproteins at this time. This could mean you have not been exposed to these viruses recently or that your immune system has not yet produced detectable antibodies.
How soon after exposure can I expect results?
Results may take several days to a couple of weeks to be processed and reported, depending on the laboratory’s workflow. Antibodies typically appear in the blood several weeks after exposure to the virus, so if you suspect recent exposure, other diagnostic tests may be needed to confirm an active infection.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy