Fluorescent Immunoassay for Anti-Vaccinia Virus Antibodies (Serum/Plasma)
This test detects antibodies to the vaccinia virus, which is used in vaccines like smallpox vaccines. It helps assess immunity or exposure to the virus.
["Checks if your body has developed immunity to vaccinia virus after vaccination or exposure."]
Key facts at a glance
- LOINC
- 7929-3
- Short code
- FLUAV Vic Ab Ser-aCnc
- Synonyms
- FLUAV Vic Ab Ser-aCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test measures the presence of antibodies specific to the vaccinia virus in your blood. Antibodies are proteins your immune system makes in response to a virus or vaccine. This helps determine if your immune system has recognized and responded to the virus.
Why It’s Ordered
Your healthcare provider may order this test if you’ve received a smallpox vaccine and want to confirm immunity, or if you’ve had potential exposure to the virus and need to monitor your immune response.
What to Expect Before the Test
No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re taking blood from a vein, you might feel a brief pinch, but it’s usually over quickly.
What to Expect During the Test
The blood sample is sent to a lab where it undergoes a fluorescent immunoassay. This process detects the antibodies in your serum or plasma using a fluorescent marker to identify the presence of vaccinia-specific antibodies.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results indicate your immune system has produced antibodies against the vaccinia virus, suggesting either prior vaccination or exposure. Negative results may mean you lack immunity and could be at risk if exposed. This test is critical for monitoring vaccine efficacy and assessing immunity in high-risk groups.
Short name
Anti-Vaccinia Virus Antibody (FIA)
Frequently asked questions
How long does it take to get results?
What does a positive result mean?
Can I get this test if I haven’t been vaccinated?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy