Skip to content

Influenza Whole Genome Sequencing by Next-Generation Sequencing (NGS) from Respiratory Specimen

Published: August 9, 2026Updated: August 16, 2026

This test analyzes the genetic material of the influenza virus in your respiratory sample to identify specific virus strains and mutations. It helps determine the best treatment and vaccination strategies.

Quick summary

["Understanding your virus type and resistance patterns can guide personalized medical decisions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85532-0
Short code
FLUAV whole genome Islt-Seq
Synonyms
FLUAV whole genome Islt-Seq
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
sequencing
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test if you have symptoms of influenza (e.g., fever, cough, fatigue) and suspect a specific strain of the virus. It’s particularly useful in outbreaks, during flu season, or when standard tests (like rapid antigen tests) are inconclusive.

How the Test Works

A small sample of your respiratory secretions (e.g., nasal swab or throat swab) is collected and sent to a lab. The lab extracts the genetic material (RNA) from the influenza virus and sequences it using advanced technology to identify the virus’s genetic sequence.

What You Should Expect

You’ll likely receive results within a few days to a week, depending on lab processing times. Your healthcare provider will discuss the findings and next steps, such as treatment options or vaccination recommendations.

What the Results Mean

Results provide detailed genetic information about the influenza virus, including its subtype (e.g., A/H3N2, B/Victoria) and potential drug resistance markers. This helps tailor treatment to the specific virus strain.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Influenza Virus Genome Sequencing

Frequently asked questions

How long does it take to get results from this test?
Results typically take 3–7 business days, depending on lab workload and processing steps. Your provider will contact you once available.
Can I get this test if I’ve already had a rapid flu test?
Yes, this test is used when rapid antigen tests are negative or inconclusive. It provides deeper genetic insights that may help confirm the virus type or detect resistance.
Is this test covered by insurance?
Coverage depends on your insurance plan and clinical indication. Check with your provider or insurance company to confirm coverage details before the test.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy