Skip to content

Flubromazolam/Creatinine [Mass Ratio] in Urine — Confirmatory Method

Published: August 9, 2026Updated: August 16, 2026

This test detects flubromazolam, a designer benzodiazepine, in urine. A creatinine ratio helps account for differences in urine concentration.

Quick summary

["A positive result indicates that flubromazolam was detected in the urine sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101159-2
Short code
Flubromazolam/Creat Ur Cfm
Synonyms
Flubromazolam/Creat Ur Cfm
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This laboratory test checks urine for flubromazolam, a benzodiazepine sometimes called a designer benzodiazepine. The result may be reported relative to urine creatinine to help account for how concentrated or diluted the specimen is.

Why might I need this test?

This test may be ordered when there is concern about nonprescribed benzodiazepine use, suspected drug impairment, or investigation of an unexplained medical or safety concern. It is often part of a broader toxicology evaluation.

How is the test performed?

A urine specimen is collected and analyzed in the laboratory. A confirmatory method is used to identify flubromazolam and distinguish it from substances that may cause an initial screening result.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory or clinician. Usually, no fasting or medication changes are required unless specifically directed; tell the care team about any medicines or supplements taken before collection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Detecting flubromazolam indicates exposure to this benzodiazepine, but it does not by itself establish the dose taken, the time of use, or whether impairment is present. A negative result cannot completely exclude exposure if testing occurs outside the detection window. Urine creatinine helps reduce the effect of differences in urine concentration, but results should still be interpreted with the clinical situation.

Short name

Urine flubromazolam test

Frequently asked questions

What is flubromazolam?
Flubromazolam is a potent benzodiazepine that is not approved for medical use in the United States. It is sometimes sold online as a designer drug or falsely represented as a research chemical.
Does a positive result mean someone was impaired?
Not necessarily. The test shows that flubromazolam was detected, but the result alone cannot determine the dose, timing, or level of impairment.
Why is the result compared with creatinine?
Urine concentration can vary widely. Creatinine is used as a marker of dilution so that results from more concentrated or dilute samples can be compared more reliably.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy