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Fibrinogen (Serum/Plasma Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen in your blood. Fibrinogen is a protein that helps blood clot and is important for preventing excessive bleeding.

Quick summary

["Fibrinogen helps your blood clot properly and supports overall blood health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
52974-3
Short code
FLUBV Ab Ser CF-aCnc
Synonyms
FLUBV Ab Ser CF-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
comp-fix
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a fibrinogen test to check for bleeding disorders, clotting problems, or conditions like liver disease, which can affect how your body produces fibrinogen. It may also be used to monitor treatment for conditions like disseminated intravascular coagulation (DIC).

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein. If you’re taking blood from a fingerstick (e.g., for a finger-prick test), no fasting is required.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are reported as a mass concentration (typically in grams per liter, g/L). Your results will be compared to a reference range provided by your healthcare provider, which may vary slightly depending on your age, sex, and overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Fibrinogen

Frequently asked questions

What causes low fibrinogen levels?
Low fibrinogen can result from liver disease (since the liver produces fibrinogen), severe infections, blood loss, or certain medications. It may also appear in conditions like DIC, where the body’s clotting system becomes overactive.
What causes high fibrinogen levels?
High fibrinogen is often linked to inflammation, infections (like sepsis), or certain cancers. It may also be seen in pregnancy or after surgery. Chronic conditions like rheumatoid arthritis can also raise fibrinogen levels.
Can diet affect fibrinogen levels?
Dietary factors like high saturated fat intake or obesity may influence inflammation, which could indirectly affect fibrinogen. However, fibrinogen is primarily produced by the liver, so diet alone is less direct than other factors like liver health or inflammation.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy