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Vitamin D Binding Protein (DBP) – Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of Vitamin D Binding Protein (DBP) in your blood. DBP helps transport vitamin D and other hormones in your body.

Quick summary

["DBP levels may be checked if you have vitamin D deficiency or other related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54241-5
Short code
FLUBV Ag Islt Ql
Synonyms
FLUBV Ag Islt Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does DBP Measure?

Vitamin D Binding Protein (DBP) is a protein in your blood that binds to vitamin D and other hormones, including calcitriol, which is the active form of vitamin D. It helps regulate calcium and phosphate metabolism, which are essential for bone health and other bodily functions. This test assesses the concentration of DBP in your serum to understand its role in hormone transport and potential implications for vitamin D status or other metabolic processes.

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms or risk factors for vitamin D deficiency, such as chronic kidney disease, malabsorption disorders, or certain medications that affect vitamin D metabolism. It may also be used in research or specialized clinical scenarios to evaluate hormone transport functions.

Common Reasons for Testing

Common reasons include monitoring vitamin D-related conditions, assessing kidney function indirectly, or investigating unexplained symptoms like bone pain, muscle weakness, or fatigue that may be linked to hormone imbalances.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if your provider specifies it. Wear a comfortable shirt and arrive at your appointment with an ID and insurance information if required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated DBP levels may be associated with certain genetic conditions or kidney diseases, while low levels could indicate underlying metabolic disturbances or vitamin D deficiency. However, DBP alone is not typically used to diagnose vitamin D deficiency; it is often measured alongside other tests like 25-hydroxy vitamin D levels. Your provider will interpret results in the context of your overall health and symptoms.

Short name

DBP

Frequently asked questions

How is DBP tested?
The test involves drawing blood from a vein in your arm. A small needle is used to collect a sample, which is then sent to a lab for analysis using an immunoassay method to measure DBP concentration in your serum.
What are the typical reference ranges?
Reference ranges for DBP can vary by lab and may not be widely standardized. Your results will be compared to your own baseline and clinical context rather than a single universal range.
Can DBP levels change with diet or supplements?
DBP levels are primarily influenced by genetic factors and kidney function. While diet and supplements may indirectly affect vitamin D status, which DBP helps transport, they do not directly alter DBP concentration in the blood.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy