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Vitamin B12 (Serum or Plasma Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of vitamin B12 in your blood. Vitamin B12 is essential for nerve function, red blood cell production, and DNA synthesis.

Quick summary

["Vitamin B12 helps prevent serious health issues like anemia or nerve damage."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
109690-8
Short code
FLUBV Ag Msmt Nph
Synonyms
FLUBV Ag Msmt Nph
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
7.35
Ref high
7.45
Critical range
7.2 N/A – 7.6 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like fatigue, weakness, numbness, or tingling in your hands and feet. It may also be done to check for vitamin deficiencies, especially in people who follow strict vegetarian or vegan diets, have certain gastrointestinal conditions, or take medications that interfere with vitamin absorption.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood. If you’re on blood thinners, let your provider know before the test.

What Happens During the Test?

A healthcare professional will collect a blood sample from a vein in your arm. The sample is then sent to a lab for analysis. Results are typically available within a few days.

What the Results Mean

Low levels of vitamin B12 can indicate deficiencies, which may require dietary changes, supplements, or medical treatment. High levels may be due to certain medical conditions or medications.

Reference range

NCBI: pH 7.35-7.45N/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Vitamin B12 deficiency can lead to serious health problems, including pernicious anemia, nerve damage, or cognitive issues. Regular monitoring is important for those at higher risk.

Short name

Vitamin B12 Level

Frequently asked questions

What causes low vitamin B12 levels?
Low vitamin B12 levels can result from poor diet, conditions affecting absorption (like pernicious anemia or celiac disease), or certain medications. Chronic conditions like Crohn’s disease or kidney disease may also contribute.
How long does it take to get results?
Results are usually ready within 2–5 business days, depending on your lab’s processing time. Your healthcare provider will discuss them with you during your follow-up visit.
Can I eat or drink anything before the test?
You can eat and drink normally before the test unless your provider instructed otherwise. Avoid alcohol for 24 hours if it may affect your blood test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy