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Bronchial Lavage Fluid Alpha-1 Antitrypsin (Mass Concentration) Probe

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Alpha-1 Antitrypsin, a protein that helps protect your lungs from damage caused by enzymes released during inflammation.

Quick summary

["Alpha-1 Antitrypsin levels in lung fluid can help diagnose or monitor lung diseases like emphysema or chronic obstructive pulmonary disease (COPD)."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105216-6
Short code
FLUBV RNA Bronch Ql NAA+probe
Synonyms
FLUBV RNA Bronch Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like persistent cough, shortness of breath, or lung-related issues that suggest lung inflammation or damage. It’s often used in patients with known genetic Alpha-1 Antitrypsin deficiency or those suspected of developing lung disease from chronic conditions like COPD.

What to Expect Before the Test

You’ll likely undergo a bronchoscopy, where a thin tube is inserted through your nose or mouth into your airways. A small amount of fluid will be collected from your lungs using gentle suction. This procedure is usually done under sedation and may cause mild discomfort but is generally safe.

What the Test Results Mean

Lower-than-normal Alpha-1 Antitrypsin levels in your lung fluid may indicate lung damage or inflammation. Higher-than-normal levels could be due to certain medical conditions or medications. Your doctor will interpret the results in the context of your overall health and symptoms.

Common Conditions Monitored

This test is primarily used to diagnose or assess Alpha-1 Antitrypsin deficiency, a genetic disorder that can lead to lung and liver problems. It may also help monitor lung disease progression in patients with conditions like COPD or chronic bronchitis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Alpha-1 Antitrypsin in Bronchial Lavage Fluid

Frequently asked questions

Alpha-1 Antitrypsin deficiency is linked to progressive lung diseases, such as emphysema, and liver diseases. Low levels in lung fluid can signal early lung damage, prompting early intervention to slow disease progression.
This test is not typically performed as a routine screening. It’s usually ordered when symptoms or a clinical suspicion of lung disease aligns with known risk factors for Alpha-1 Antitrypsin deficiency or related conditions.
The test involves collecting fluid from your lungs during a bronchoscopy, which is generally safe but may have mild risks like temporary discomfort or infection. Follow-up care depends on your doctor’s findings and recommendations.
Your results will be reviewed by a healthcare provider who will discuss them with you based on your medical history, symptoms, and other test results. They may recommend lifestyle changes, treatments, or further testing if needed.
No special preparation is usually required, but you may need to avoid certain medications or foods for a short time before the procedure. Always follow your doctor’s instructions for the best accuracy of results.
If you have questions about the test results or next steps, discuss them with your healthcare provider. They can clarify what the findings mean for your health and treatment plan.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy