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Folate (Vitamin B9) in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of folate, a B vitamin essential for DNA synthesis and red blood cell production, in your blood.

Quick summary

["Folate levels help assess nutritional status and detect deficiencies that may affect pregnancy or anemia."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
76080-1
Short code
FLUBV RNA Nph Ql NAA+probe
Synonyms
FLUBV RNA Nph Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for folate deficiency, monitor vitamin intake, especially during pregnancy, or evaluate conditions like anemia or malabsorption disorders.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If fasting is required (sometimes for related tests), follow your provider’s instructions.

What the Results Mean

Low levels may indicate poor diet, malabsorption, or certain medical conditions. High levels could suggest folate supplements or liver disease. Results are interpreted by your provider in context with your health.

Common Conditions Linked to Folate Levels

Deficiencies are often linked to anemia, pregnancy complications, or conditions like alcoholism or Crohn’s disease. Elevated levels may signal over-supplementation or liver issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Folate plays a critical role in cell growth and preventing neural tube defects in pregnancy. Deficiencies can also contribute to fatigue, weakness, or neurological symptoms.

Short name

Serum Folate

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may suggest it if you have symptoms like fatigue, pale skin, or if you’re pregnant, have a history of anemia, or take medications that affect folate absorption.
What does a low folate level mean?
A low result may mean you’re not getting enough folate from food or supplements, which could affect how your body produces red blood cells or DNA. Your provider will discuss next steps, like diet changes or supplements.
Can folate levels change with diet?
Yes, diet plays a key role. Foods like leafy greens, beans, and fortified cereals are rich in folate. If you suspect dietary changes are affecting your levels, talk to your provider about adjustments.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy