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Protein Electrophoresis (Serum) with Bromocresol Green (BCG) Dye Shift Analysis

Published: August 9, 2026Updated: August 16, 2026

This test measures the distribution of different proteins in your blood, often used to identify abnormalities in protein levels that may suggest conditions like multiple myeloma, liver disease, or kidney problems.

Quick summary

["Helps diagnose and monitor protein-related disorders by analyzing blood protein patterns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
105234-9
Short code
FLUBV RNA Spt Ql NAA+probe
Synonyms
FLUBV RNA Spt Ql NAA+probe
Category
chemistry
Sample
sputum
Container
Sterile sputum container
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
CPT
85610
SNOMED
396252006
Specimen volume
3-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may order this test to investigate symptoms such as unexplained weight loss, fatigue, swelling, or changes in urine appearance. It’s also used to monitor conditions like multiple myeloma, where abnormal protein production is common, or to check for liver or kidney function issues that affect protein balance.

How the Test Works

A small blood sample is taken and separated into different protein fractions using electrophoresis. Bromocresol Green dye binds to proteins, shifting colors based on their size and charge. This shift helps identify which proteins are present in higher or lower amounts than expected.

Sample Collection and Preparation

You’ll have a needle inserted into a vein (usually in your arm) to draw blood. The sample is then processed in a lab to separate proteins and analyze their distribution.

What to Expect Before the Test

No special preparation is needed, but inform your doctor about any medications or conditions that might affect protein levels (e.g., kidney disease, liver issues, or recent infections).

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: sputum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Protein Electrophoresis (BCG)

Frequently asked questions

What does a high or low protein result mean?
Results can’t be interpreted alone—they’re compared to your medical history and other test findings. High levels of certain proteins may signal conditions like inflammation or liver disease, while abnormal spikes (e.g., monoclonal bands) could indicate multiple myeloma or other plasma cell disorders. Your doctor will discuss findings with you.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on lab processing times. Follow-up with your healthcare provider to review findings and next steps.
Can I eat or drink before this test?
No special diet is required, but avoid heavy meals or alcohol before the blood draw to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy