Skip to content

Serum or plasma concentration of free vanillylmandelic acid (VMA) measured by immunoassay

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a specific chemical called free vanillylmandelic acid (VMA) in your blood. VMA is a breakdown product of certain hormones produced by the adrenal glands.

Quick summary

["VMA helps assess adrenal gland function and detect conditions like neuroblastoma or pheochromocytoma."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86572-5
Short code
FLUBV RNA Tiss Ql NAA+probe
Synonyms
FLUBV RNA Tiss Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect an adrenal gland tumor or other conditions affecting hormone production. It can also be part of evaluating symptoms like headaches, high blood pressure, or unexplained weight changes that might suggest hormonal imbalances.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, similar to other routine blood tests. If you’re on blood-thinning medication, let your healthcare provider know before the test.

What the Test Results Mean

Results are interpreted by your doctor based on your overall health and symptoms. Elevated levels may indicate conditions like neuroblastoma (a childhood cancer) or pheochromocytoma (a rare tumor). Lower levels might raise concerns in certain contexts, but results alone don’t diagnose conditions.

Common Conditions Monitored

This test is often used alongside other tests to diagnose or monitor adrenal gland tumors, neuroblastoma, or other conditions affecting hormone secretion. It’s not typically a standalone test for most conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Free VMA levels can be elevated in patients with tumors that produce excess catecholamines (like pheochromocytoma or neuroblastoma). Doctors use these results to guide further testing, such as imaging or genetic evaluations, to identify the underlying cause of symptoms. However, VMA alone isn’t diagnostic—it’s part of a broader assessment.

Short name

Free VMA

Frequently asked questions

What does a high or low VMA level indicate?
A high VMA level may suggest conditions like pheochromocytoma or neuroblastoma, but results depend on clinical context. Your doctor will review your symptoms, other test results, and medical history before interpreting the meaning.
Can diet or medications affect VMA test results?
Certain foods (like tyramine-rich foods) or medications (e.g., certain antidepressants) can temporarily affect VMA levels. If you’re taking these, your doctor may advise avoiding them for 24–48 hours before testing to get an accurate result.
How often should I get this test?
Frequency depends on your diagnosis and treatment plan. If you’re being monitored for a known condition, your doctor will schedule follow-up tests as needed. For screening, this test isn’t typically recommended unless symptoms suggest a need.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy