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Fluconazole Concentration in Serum or Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fluconazole, a medication used to treat fungal infections, in your blood.

Quick summary

["Helps determine if your fluconazole dose is working effectively and if adjustments are needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73377-4
Short code
Fluconazole ind plt IgM SerPl Ql FC
Synonyms
Fluconazole ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking fluconazole to treat or prevent fungal infections, such as candidiasis (yeast infections). It helps monitor drug levels to ensure proper dosing and avoid side effects.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast before the draw, but this depends on your provider’s instructions. A healthcare professional will collect a blood sample from a vein in your arm.

What the Test Results Mean

Results are used to guide treatment decisions, such as adjusting your dose if levels are too high or low. Your provider will interpret the results in the context of your medical history and symptoms.

Possible Side Effects or Risks

While rare, fluconazole can cause mild side effects like nausea or stomach upset. Blood tests, including this one, help ensure your body is handling the medication safely.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fluconazole levels in your blood help prevent toxicity (e.g., kidney or liver issues) and confirm the drug is effective. Low levels may mean the infection isn’t fully treated, while high levels could signal unnecessary exposure.

Short name

Fluconazole Level

Frequently asked questions

Why was I asked to have this test?
Your doctor may have ordered it to check if your fluconazole dose is working properly, especially if you’re taking it for a fungal infection or long-term prevention.
What does a low or high fluconazole level mean?
Low levels might mean the infection isn’t fully treated, while high levels could indicate the drug is too strong for your body. Your provider will discuss these results with you.
Can I eat or drink before this test?
Check with your provider—some tests require fasting, but others do not. Follow their specific instructions for the best results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy