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Fluconazole Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fluconazole, a medication used to treat fungal infections, in your blood serum. It helps doctors check if your dose is working properly.

Quick summary

["This test helps ensure your antifungal medication is at the right level for effective treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73020-0
Short code
Fluconazole (neut) IgG SerPl Ql FC
Synonyms
Fluconazole (neut) IgG SerPl Ql FC
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking fluconazole to treat infections like yeast infections (e.g., thrush, vaginal or skin infections), or if you have a fungal infection that doesn’t respond well to other treatments. It’s also used to monitor levels in people with kidney problems, who may need dose adjustments.

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The test is quick and typically done in a lab setting. If you’re on a long-term antifungal medication, your doctor may schedule this test during or after your treatment.

How the Test Works

Blood is collected and sent to a lab where it’s analyzed to measure the exact amount of fluconazole present. The lab uses a sensitive method to detect even small traces of the medication in your bloodstream.

What the Results Mean

Results show the concentration of fluconazole in your blood. Your doctor will compare these results to your treatment plan to decide if your dose needs to be changed. Too little may mean the infection isn’t fully treated, while too much could cause side effects.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fluconazole Level

Frequently asked questions

How often should I have this test?
The frequency depends on your treatment plan. For short-term courses, your doctor may check levels once or twice. For long-term use or in people with kidney issues, tests might be done more often, such as every few weeks or months, to adjust your dose safely.
What if my results are too high or too low?
If your fluconazole levels are too high, your doctor may reduce your dose or switch to a different medication to avoid side effects like nausea, headaches, or allergic reactions. If levels are too low, your dose may be increased to ensure the infection is fully treated.
Can I drink alcohol before this test?
No, it’s best to avoid alcohol before your blood test, as it may affect your results or cause side effects. Follow your doctor’s instructions for any restrictions related to your specific medication and health condition.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy