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Fluconazole Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the antifungal medication fluconazole in your blood serum. It helps doctors monitor your dose and ensure the drug is working effectively.

Quick summary

["This test helps adjust your fluconazole dose for better treatment of fungal infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44579-1
Short code
FLUCV Ab Ser Ql
Synonyms
FLUCV Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking fluconazole to treat or prevent fungal infections, such as yeast infections (e.g., candidiasis). It’s also used in patients with kidney issues or those taking other medications that interact with fluconazole to check levels and avoid toxicity.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or vein to draw blood. If you’re on long-term fluconazole, your provider may check levels periodically to adjust your dose.

How the Test Works

A blood sample is taken and sent to a lab. The lab uses a sensitive method (likely immunoassay or chemiluminescent immunoassay) to measure the exact amount of fluconazole in your serum.

Possible Results and Interpretation

Results are compared to your specific dose and kidney function. Low levels may mean your dose isn’t working well, while high levels could indicate toxicity or improper dosing. Your provider will discuss these results with you.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Fluconazole Level

Frequently asked questions

How often should I have this test?
Your provider will decide based on your treatment plan, kidney function, and how long you’ve been on fluconazole. Regular checks may be needed if you have kidney problems or take other medications that interact with fluconazole.
What does a low or high fluconazole level mean?
A low level might mean your dose isn’t enough to fight the infection, while a high level could signal side effects or incorrect dosing. Your provider will explain what your results mean in your context.
Can I eat or drink before this test?
You can eat and drink normally unless your provider gives specific instructions. Avoid alcohol or other medications that might affect fluconazole levels before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy