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Fluconazole Concentration in Serum (Pharmacokinetic)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the antifungal medication fluconazole in your blood serum to help determine how well your body is processing it.

Quick summary

["Understanding your fluconazole levels helps doctors adjust your dose for better treatment effectiveness and safety."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22368-5
Short code
FLUCV Ab Titr Ser
Synonyms
FLUCV Ab Titr Ser
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking fluconazole (a medication used to treat fungal infections) and want to check how your body is handling the drug. It’s often done during treatment to ensure proper dosing, especially if you have kidney issues or take other medications that interact with fluconazole.

How the Test Works

A blood sample is taken from a vein in your arm. The sample is sent to a lab where fluconazole levels are measured using a sensitive chemical test (immunoassay). This helps track how much of the drug is present in your bloodstream at a given time.

What to Expect Before the Test

No special preparation is needed for this test. You may have a small bruise or slight discomfort at the injection site, but it usually goes away quickly. If you’re on blood thinners or have a history of bleeding disorders, let your doctor know before the test.

What the Results Mean

Results show the concentration of fluconazole in your blood. Low levels might mean the drug isn’t working as intended, while very high levels could indicate kidney problems or improper dosing. Your doctor will interpret the results in the context of your medical history and treatment plan.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fluconazole levels help prevent dangerous drug levels that could cause side effects like kidney damage, liver issues, or drug interactions. Proper monitoring ensures the medication is effective against fungal infections while minimizing risks. This test is critical for patients with weakened immune systems, kidney disease, or those taking other medications that interact with fluconazole.

Short name

Fluconazole Level

Frequently asked questions

What causes fluconazole levels to be checked?
Fluconazole levels are checked to monitor how your body processes the medication, especially if you have kidney problems, take other drugs that interact with fluconazole, or if your infection isn’t improving as expected.
How often should fluconazole levels be tested?
The frequency depends on your treatment plan. Your doctor may order tests during the first few weeks of treatment or if you develop side effects. Some patients need ongoing monitoring, especially if they have kidney issues or take multiple medications.
Can fluconazole levels be affected by diet or other medications?
Yes, certain foods, supplements, or other medications (like some antibiotics or antifungals) can affect fluconazole levels. Always tell your doctor about all medications, herbs, or dietary changes before starting fluconazole.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy