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Fluconazole Concentration in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the antifungal medication fluconazole in your blood serum. It helps your healthcare provider monitor your dose and adjust it if needed.

Quick summary

["This test ensures your fluconazole levels stay within safe ranges for effective treatment and to avoid side effects."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5231-6
Short code
FLUCV Ab Titr Ser CF
Synonyms
FLUCV Ab Titr Ser CF
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
comp-fix
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test if you’re taking fluconazole to treat or prevent fungal infections, such as yeast infections (e.g., thrush or vaginal candidiasis). It helps track how well your body is processing the medication and whether your dose needs adjustment, especially if you have kidney issues or take other medications that interact with fluconazole.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw a blood sample. The process is quick and usually painless. If you’re on blood thinners or have a history of bleeding issues, let your doctor know before the test.

What Happens During the Test?

A healthcare professional will collect a blood sample from your arm or vein. The sample is then sent to a lab where it’s analyzed using a sensitive immunoassay method to measure fluconazole levels.

What Do the Results Mean?

Results are typically reported in micrograms per milliliter (mcg/mL). Your doctor will interpret the results in relation to your medical condition, dose, and other medications you’re taking. Low levels may indicate the medication isn’t working effectively, while high levels could signal toxicity or improper dosing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fluconazole is used to treat fungal infections, and maintaining appropriate blood levels is critical. Low levels may mean the infection isn’t fully controlled, while dangerously high levels can cause side effects like nausea, headaches, or liver issues. Regular monitoring helps prevent these risks and ensures the medication is working as intended.

Short name

Fluconazole Level

Frequently asked questions

How often is this test typically done?
The frequency depends on your treatment plan. For most patients, a single test may be done shortly after starting fluconazole or if symptoms persist. If you have kidney problems or take other medications that interact with fluconazole, your doctor may order tests more often, such as every few weeks.
What if I miss my scheduled test?
If you miss your appointment, contact your healthcare provider immediately. They may need to reschedule or adjust your treatment plan based on your fluconazole levels. Skipping tests can lead to ineffective treatment or potential side effects.
Can I drink alcohol before this test?
Avoid alcohol before your test, as it may affect your liver function and could influence fluconazole metabolism. If you’re unsure, ask your doctor or pharmacist for guidance tailored to your treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy