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Fluoride and Creatinine, Urine

Published: August 9, 2026Updated: August 16, 2026

Measures fluoride in urine along with creatinine, which helps account for differences in urine concentration when assessing fluoride exposure.

Quick summary

["This test can help evaluate fluoride exposure while considering how concentrated the urine sample is."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
13475-9
Short code
Fluoride/Creat Ur
Synonyms
Fluoride/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of fluoride and creatinine in a urine sample. Fluoride is a mineral found in drinking water, toothpaste, and some supplements, while creatinine is a waste product made by the muscles and is commonly used to evaluate how concentrated the urine is.

Why might I need this test?

A clinician may order this test to assess recent fluoride exposure or monitor someone who receives fluoride-containing treatments or supplements. Measuring creatinine at the same time helps distinguish changes in fluoride excretion from changes caused by variations in urine concentration.

How is the test performed?

A urine sample is collected and analyzed in a laboratory for fluoride and creatinine. Depending on the order, the sample may be a single collection or a timed collection, so follow the collection instructions provided by the laboratory.

How do I prepare for the test?

Follow the laboratory's instructions regarding the type and timing of urine collection. Tell the clinician about fluoride-containing toothpaste or mouth rinses, supplements, medications, and the source of your drinking water, because these can affect the result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated urine fluoride result may indicate increased fluoride exposure from water, dental products, supplements, or other sources. Interpretation depends on intake, timing, urine concentration, and clinical circumstances, so an abnormal result should be discussed with a healthcare professional.

Short name

Urine Fluoride and Creatinine

Frequently asked questions

Does this test show how much fluoride I have in my body?
It shows fluoride excreted in urine, which can help estimate recent exposure but does not directly measure the body's total fluoride content.
Why is creatinine measured with urine fluoride?
Creatinine helps account for how concentrated the urine is. This allows the laboratory to compare fluoride levels more meaningfully across samples.
Can toothpaste or supplements affect the result?
Yes. Fluoride-containing toothpaste, mouth rinses, supplements, and certain medicines may influence urine fluoride levels, particularly soon after use.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy