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Folate in Blood (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of folate, a type of B vitamin, in your blood. Folate is important for cell growth and red blood cell production.

Quick summary

["Folate helps prevent birth defects and supports overall health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
2282-2
Short code
Folate Bld-mCnc
Synonyms
Folate Bld-mCnc
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
2.7
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to check for folate deficiency, especially if you have symptoms like fatigue, weakness, or unusual bleeding. It can also be part of screening for conditions like anemia or pregnancy-related complications.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s drawn from fasting blood. Bring any medications or supplements you’re taking to your appointment.

How the Test Is Performed

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it usually doesn’t cause discomfort. The blood is then sent to a lab for analysis.

What the Results Mean

Results are compared to standard reference ranges for folate levels in blood. Low levels may indicate deficiency, while very high levels could suggest certain medical conditions or supplements.

Reference range

NCBI: Folate 2.7-17.0 ng/mLN/A

Specimen: whole-blood

Fasting for 8-12 hours preferred for some tests. Inform about supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Folate Level

Frequently asked questions

What causes low folate levels?
Folate deficiency can result from poor diet (low intake of leafy greens, fortified foods), alcohol use, certain medications (like anticonvulsants), or malabsorption issues (e.g., celiac disease). Pregnancy or rapid growth phases (like childhood) may also deplete stores faster.
What symptoms might I experience if my folate is low?
Symptoms of low folate may include fatigue, pale or tired-looking skin, shortness of breath, mouth sores, or unusual bleeding. Neurological symptoms like memory problems or mood changes can also occur in severe cases.
How is folate deficiency treated?
Treatment typically involves increasing folate-rich foods (spinach, beans, fortified cereals) or supplements if needed. Your doctor may prescribe oral folic acid or intravenous supplements for deficiency-related complications.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy