Skip to content

Folate in Serum (Mass Concentration)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of folate, a B vitamin, in your blood serum. Folate is important for DNA synthesis, red blood cell production, and overall cell health.

Quick summary

["Folate helps prevent birth defects and supports energy levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
109569-4
Short code
Folate Msmt Bld
Synonyms
Folate Msmt Bld
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
2.7
Ref high
17
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a serum folate test to check for deficiencies, monitor treatment for conditions like anemia, or assess nutritional status. It’s also used in pregnancy to screen for neural tube defects in a baby.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if your lab requires it. Bring any medications you’re taking, as some (like certain antacids) can affect results.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but the process is quick and usually painless. The blood is then sent to a lab for analysis.

What the Results Mean

Low folate levels may indicate poor diet, malabsorption issues, or certain medical conditions. High levels could suggest liver disease, folate supplements, or other metabolic factors. Your results will be compared to standard reference ranges provided by your lab.

Reference range

NCBI: Folate 2.7-17.0 ng/mLN/A

Specimen: whole-blood

Fasting for 8-12 hours preferred for some tests. Inform about supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Folate

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow up with your provider if you have questions about your results.
Can folate levels change with diet?
Yes, folate intake from foods like leafy greens, beans, and fortified cereals can affect your levels. Avoid sudden changes in supplement use, as they may impact test accuracy.
Is fasting required for this test?
Sometimes, but it’s not always mandatory. Always check with your lab or provider before the test to confirm any specific instructions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy