Folate in Serum (Mass Concentration)

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms of folate deficiency, such as fatigue, weakness, or unusual bruising. It may also be used to monitor folate levels in people with certain medical conditions, like alcoholism, poor diet, or pregnancy. Sometimes, it’s checked alongside other blood tests to evaluate overall nutritional health.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it’s part of a broader blood workup, but this depends on your healthcare provider’s instructions. Bring any medications you’re taking to your appointment.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but the procedure is quick and usually painless. The blood sample is then sent to a lab for analysis.

What Are the Results Mean?

Results are compared to a reference range for healthy adults, but exact values can vary by lab. Low levels may indicate poor nutrition, certain medical conditions, or increased needs (e.g., pregnancy). High levels might suggest folate supplements or certain medications.