Serum/plasma free total protein concentration (24-hour urinary collection)
This test measures the amount of protein that appears in your urine over a full day. It helps assess kidney function and detect protein loss, which can signal conditions like kidney disease or other health issues.
["This test helps monitor kidney health and identify protein loss in urine over time."]
Key facts at a glance
- LOINC
- 111902-3
- Short code
- Frst apprch mthd Blry tr Endscpy
- Synonyms
- Frst apprch mthd Blry tr Endscpy
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- endoscopy
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if they suspect kidney problems, such as nephrotic syndrome, glomerulonephritis, or other conditions causing abnormal protein excretion. It can also be used to monitor chronic kidney disease or track responses to treatments.
What to Expect Before the Test
You’ll need to collect all urine for 24 hours, typically starting after midnight on one day and ending the same time the next day. Drink plenty of water to ensure adequate urine volume. Avoid certain medications or foods that might interfere with results (consult your doctor for specifics).
How the Test Works
Your urine sample is analyzed to measure the total protein content. The test quantifies how much protein is excreted daily, which is compared to standard reference values to identify abnormalities.
Possible Results and What They Mean
Higher-than-normal protein levels in urine may indicate kidney damage, inflammation, or other systemic conditions. Lower-than-normal levels are less common but could suggest dehydration or certain metabolic disorders. Your doctor will interpret results in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
24-Hour Urinary Free Protein
Frequently asked questions
What causes elevated protein in urine?
What if my protein levels are normal?
Can diet affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy