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Fructosamine (Serum)

Published: August 9, 2026Updated: August 17, 2026

This test measures the average blood sugar levels over the past two to three weeks by tracking glycated proteins, reflecting how your body has managed glucose over time.

Quick summary

["Helps assess long-term blood sugar control, especially useful for monitoring diabetes management."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
53550-0
Short code
Fructosamine/Prot SerPl-Rto
Synonyms
Fructosamine/Prot SerPl-Rto
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
200
Ref high
285
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for You

Fructosamine is useful for patients with diabetes or prediabetes because it provides a snapshot of your blood sugar control over a longer period than a single glucose measurement. It helps doctors track trends and adjust treatment plans accordingly.

How the Test Works

Your blood sample is analyzed to detect glycated proteins—specifically, proteins that have bonded with excess sugar. This test doesn’t require fasting and can be done anytime, making it convenient for regular monitoring.

Sample Collection and Preparation

A small blood sample is drawn from your arm, similar to other blood tests. The sample is processed in the lab to measure the glycated protein levels, which are then reported as a percentage or concentration.

What to Expect Before the Test

No special preparation is needed. You can eat, drink, or take medication as usual. If you have a history of bleeding disorders or are on blood thinners, let your healthcare provider know before the test.

Reference range

NCBI: Fructosamine 200-285 µmol/LN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fructosamine Level

Frequently asked questions

Fructosamine levels can indicate whether your blood sugar has been consistently high or low over time. Elevated levels may suggest poor diabetes control, while lower levels might indicate periods of lower glucose. It’s particularly helpful for patients who may not experience symptoms of hyperglycemia or hypoglycemia.
Fructosamine tests are typically used alongside other glucose-related tests (like HbA1c) to provide a more comprehensive picture of your blood sugar management. They can help adjust medications or lifestyle changes to improve long-term health outcomes.
How Often Should I Get This Test?
Your healthcare provider will determine the frequency based on your medical history, current treatment plan, and overall health. For most people with diabetes, this test may be recommended every few months to monitor progress.
What Are Normal Results?
There are no strict numeric reference ranges provided here, as they can vary by lab and patient factors. Your results will be interpreted by your healthcare provider in the context of your overall health and medical history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy