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Urine Fructose-to-Creatinine Ratio

Published: August 9, 2026Updated: August 16, 2026

Measures urine fructose relative to urine creatinine to assess how much fructose is being excreted while accounting for urine concentration.

Quick summary

["This urine test helps evaluate fructose metabolism and may identify increased urinary fructose."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34309-5
Short code
Fructose/Creat Ur-sRto
Synonyms
Fructose/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of fructose in urine relative to the amount of creatinine. Creatinine is used as a marker of urine concentration, so the ratio can help show whether fructose excretion is higher than expected.

Why might I need this test?

Your clinician may order this test when symptoms suggest a problem with fructose or carbohydrate metabolism. It can also be used to follow dietary fructose intake or investigate abnormal urinary findings.

How is the test performed?

Fructose and creatinine are measured in a urine sample, and the laboratory calculates their ratio. Depending on your clinician's instructions, this may be a single urine collection or a timed collection such as a 24-hour urine collection.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional or laboratory. Keep dietary and medication habits as usual unless your clinician specifically asks you to change them, and accurately report the collection time and any missed samples.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine fructose/creatinine ratio

Frequently asked questions

Does this test require fasting?
Fasting is not always required, but your clinician may request a fasting or timed collection in certain situations. Follow the specific instructions given with your urine collection kit.
Why is creatinine included in the result?
Creatinine helps show how concentrated the urine is. Dividing or comparing fructose with creatinine makes the result less dependent on variations in urine volume.
What symptoms may lead to this test being ordered?
It may be considered when abdominal pain, vomiting, poor feeding, or other symptoms occur after foods containing fructose or sucrose. Your clinician will decide whether this test is appropriate based on your history and examination.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy