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Fructosamine (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the average blood sugar levels over the past 2–3 weeks by tracking glycated proteins, reflecting how your body has managed glucose levels recently.

Quick summary

["Helps assess long-term blood sugar control in diabetes or prediabetes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
110017-1
Short code
Fructose Msmt Smn
Synonyms
Fructose Msmt Smn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a fructosamine test if you have diabetes or are at risk for it. It’s useful for monitoring how well your blood sugar is controlled over time, especially if you don’t have access to frequent hemoglobin A1c tests or if you’re using insulin and need to track recent glucose trends.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed using an immunoassay method to measure the glycated proteins in your serum.

What Do the Results Mean?

Results don’t come with a standard reference range, but they’re compared to your baseline or trends over time. Higher levels may indicate poor blood sugar control, while lower levels might suggest improved management.

What Are the Benefits?

Unlike hemoglobin A1c, which reflects average glucose over 2–3 months, fructosamine gives a snapshot of glycation over the past 2–3 weeks, useful for recent adjustments in treatment (e.g., insulin dose changes).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Fructosamine is particularly valuable for patients using insulin or other glucose-lowering medications, as it provides real-time feedback on how well their current regimen is controlling blood sugar. It’s also useful for monitoring in conditions like chronic kidney disease or liver disease, where protein metabolism can affect glycation levels. However, it’s less commonly used than hemoglobin A1c for routine screening due to its shorter half-life and variability with certain medications or conditions.

Short name

Fructosamine Level

Frequently asked questions

How often should I expect this test?
The frequency depends on your healthcare provider’s recommendations. Some patients with diabetes may get it monthly or every few months to track recent glucose trends, while others may only need it periodically.
Can I eat or drink before this test?
No special preparation is needed. You can eat and drink normally, as fructosamine measures glycated proteins in your blood, not fasting glucose levels.
Will this test affect my insulin or medication doses?
Results from fructosamine can help your provider adjust insulin or other medications to improve blood sugar control. However, they’re not used alone to determine doses—your provider will consider this test alongside other factors like symptoms, symptoms, and other lab results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy