Serum Fructosamine
This test measures the average blood sugar levels over the past 2–3 weeks by tracking glycated proteins, reflecting how your body has managed glucose over time.
["Helps assess long-term blood sugar control in diabetes or prediabetes."]
Key facts at a glance
- LOINC
- 10574-2
- Short code
- Fructose Smn-sCnc
- Synonyms
- Fructose Smn-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters
Unlike hemoglobin A1c, which measures blood sugar over roughly 3 months, fructosamine gives a snapshot of recent glucose exposure. It’s useful for monitoring treatment in people with diabetes who may have frequent blood sugar fluctuations or certain blood disorders that affect hemoglobin stability.
How It Works
Fructosamine levels rise when blood sugar is consistently high because glucose attaches to proteins in your blood. The test detects these glycated proteins using an immunoassay method, providing a direct measure of your body’s average glucose exposure over a shorter timeframe.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample drawn from a vein, similar to other routine blood tests. Results are typically reported in mass concentration units (mg/dL or µmol/L).
What the Results Mean
Higher fructosamine levels often indicate poor blood sugar control, particularly in people with diabetes. Lower levels may suggest consistently lower glucose levels, though this isn’t always the case. Always discuss results with your healthcare provider to interpret them in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Fructosamine Level
Frequently asked questions
How often should I get this test?
Can fructosamine replace hemoglobin A1c?
What causes fructosamine levels to change?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy