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Follicle-Stimulating Hormone to Creatinine Ratio, 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

Measures follicle-stimulating hormone (FSH) relative to creatinine in urine collected for 24 hours. It may help assess hormone activity in fertility or reproductive evaluations.

Quick summary

["This test measures FSH relative to creatinine in a 24-hour urine collection."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
29155-9
Short code
FSH/Creat 24h Ur-Rto
Synonyms
FSH/Creat 24h Ur-Rto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Ref low
3.5
Ref high
12.5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83001
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures follicle-stimulating hormone (FSH), a pituitary hormone that helps regulate ovulation and sperm production, in urine collected over 24 hours. The result may be expressed as a ratio to urinary creatinine, which helps account for differences in urine concentration.

Why might I need this test?

A clinician may order this test as part of an evaluation of fertility, menstrual changes, or reproductive function. FSH levels can vary during the menstrual cycle and with age, so the result is interpreted alongside medical history and other fertility tests.

How is the test performed?

You collect all urine produced during a full 24-hour period in the container provided by the laboratory. The laboratory then measures FSH and creatinine and may calculate their ratio.

How do I prepare for the test?

Follow the laboratory's collection instructions carefully, including the starting and ending times. Do not include urine collected before the collection period, and ask the laboratory whether the container should be refrigerated during the 24 hours.

Reference range

Follicular: 3.5-12.5 mIU/mLN/A

Specimen: urine

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An FSH result that is higher than expected may suggest reduced ovarian reserve or primary ovarian insufficiency, depending on the clinical context. A lower result can occur with normal reproductive function, hormonal contraception, or other conditions that suppress pituitary signaling. The 24-hour urine FSH-to-creatinine ratio must be interpreted by a clinician because urinary hormone levels vary with collection completeness, urine concentration, medications, and reproductive status.

Short name

24-Hour Urine FSH/Creatinine Ratio

Frequently asked questions

Is this the same as a blood FSH test?
No. This test measures FSH in urine collected over 24 hours rather than in a blood sample, and the result may be reported relative to urinary creatinine.
Why is a 24-hour urine collection needed?
It captures hormone excretion over a full day and is less dependent on a single random urine sample. Complete collection is important for an accurate result.
Can medications affect the result?
Yes. Hormonal contraceptives, fertility medicines, hormone therapy, and some other medications can affect FSH levels. Tell your clinician about medicines and supplements you have used.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy