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FSH (Follicle Stimulating Hormone) – Serum, Quantitative

Published: August 9, 2026Updated: August 16, 2026

This blood test measures the amount of follicle-stimulating hormone (FSH) in your serum. FSH is a hormone produced by the pituitary gland that plays a key role in reproductive health, particularly in regulating the menstrual cycle and sperm production.

Quick summary

["FSH helps assess fertility, hormone balance, and potential issues with ovulation or egg development in women, or sperm production in men."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
50481-1
Short code
FSH sp5 SerPl-aCnc
Synonyms
FSH sp5 SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
3.5
Ref high
12.5
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
83001
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your doctor may order an FSH test to evaluate fertility problems, such as irregular menstrual cycles, difficulty becoming pregnant, or low sperm counts. It can also help diagnose conditions like premature ovarian insufficiency (POI) in women or hypogonadism in men. Sometimes, FSH levels are checked alongside other hormones like luteinizing hormone (LH) or estrogen/testosterone to get a full picture of reproductive health.

What to Expect Before the Test

No special preparation is usually needed for an FSH blood test. You may be asked to fast for 8–12 hours before the draw, but this depends on your doctor’s instructions. On the day of the test, avoid strenuous activity or caffeine, as these can sometimes affect hormone levels temporarily.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a slight pinch, but the procedure is quick and typically painless. The blood sample is then sent to a lab for analysis.

What Do Your Results Mean?

FSH results are interpreted based on your age, sex, and medical history. High or low levels can signal underlying conditions, but your doctor will discuss the results in the context of your overall health. For example, elevated FSH in women may indicate early menopause, while elevated FSH in men could suggest low testosterone or other hormonal imbalances.

Reference range

Follicular: 3.5-12.5 mIU/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance of FSH Levels

Short name

FSH Level

Frequently asked questions

What Causes High FSH Levels?
High FSH levels can occur due to conditions affecting the ovaries (e.g., polycystic ovary syndrome, POI), pituitary gland dysfunction, or genetic factors. In men, high FSH may signal low sperm production or reduced testosterone. Your doctor will consider other symptoms and tests to determine the cause.
What Causes Low FSH Levels?
Low FSH levels may result from pituitary tumors, hypothyroidism, or certain medications that suppress hormone production. In women, low FSH can sometimes indicate early puberty or rare genetic disorders. In men, it may suggest conditions like Klinefelter syndrome or undiagnosed hypogonadism.
Can FSH Levels Change Over Time?
Yes, FSH levels naturally fluctuate with age, especially in women, due to the aging ovaries. For example, FSH tends to rise after menopause. In men, FSH levels may also vary with stress, illness, or certain medications. Your doctor will track changes over time if needed for diagnosis or treatment planning.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy