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Fungal nucleic acid detection in skin lesion biopsy by qualitative probe-based assay

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of fungal DNA in a sample taken from your skin lesion, helping doctors identify infections like ringworm or athlete’s foot.

Quick summary

["A simple test to detect fungal infections in your skin that may guide treatment options."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91084-4
Short code
Fungal 18s rRNA gene Derm Ql NAA+probe
Synonyms
Fungal 18s rRNA gene Derm Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may recommend this test if you have a persistent or suspicious skin rash, redness, or lesion that doesn’t improve with typical treatments. It helps confirm whether a fungal infection is causing your symptoms before starting antifungal medications.

How the Test Works

A small sample of your skin lesion is collected and tested for fungal genetic material using a specialized probe. This method is highly sensitive and doesn’t require culturing the fungus, making it quicker than traditional methods.

Sample Collection

You’ll likely have a small sample taken by a healthcare provider using a swab or biopsy tool. The sample is then processed in the lab to detect fungal DNA.

What to Expect After the Test

Results are typically available within a few days. If the test confirms a fungal infection, your provider will work with you to choose the best treatment plan, which may include topical or oral antifungal medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Fungal Skin Probe Test

Frequently asked questions

What does a positive result mean?
A positive result indicates the presence of fungal DNA in your skin lesion, strongly suggesting a fungal infection. This can help guide treatment decisions to target the infection effectively.
What does a negative result mean?
A negative result means no fungal DNA was detected in the sample, which may mean your symptoms are caused by something else (like bacteria, virus, or non-infectious skin conditions). Further evaluation may still be needed.
How often should I get this test?
This test is usually done once if needed for diagnosis. If you have recurring skin issues, your provider may recommend it again if symptoms persist or worsen.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy