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Fungal nucleic acid detection by real-time polymerase chain reaction (PCR) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of fungal DNA in your blood, helping doctors identify infections caused by fungi like Candida or Cryptococcus.

Quick summary

["Detects fungal infections early with a simple blood sample."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91083-6
Short code
Fungal 18s rRNA gene Islt Ql NAA+probe
Synonyms
Fungal 18s rRNA gene Islt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, fatigue, or organ dysfunction that could suggest a fungal infection. It’s also used in patients with weakened immune systems (e.g., after chemotherapy, organ transplant, or HIV) who are at higher risk for fungal infections.

How the Test Works

A small blood sample is taken and tested for specific fungal genetic material using PCR. This method is highly sensitive and can detect even trace amounts of fungi in your bloodstream.

What to Expect Before the Test

No special preparation is needed. You may have a slight bruise or discomfort at the injection site, but the blood draw itself is quick and painless.

What to Expect After the Test

You can resume normal activities immediately. If you experience unusual bleeding or excessive pain, contact your provider right away.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for diagnosing fungal bloodstream infections, which can be life-threatening if untreated. Early detection allows for prompt treatment with antifungal medications, improving outcomes in high-risk patients.

Short name

Fungal PCR (Serum/Plasma)

Frequently asked questions

How long does it take to get results?
Results are typically available within 24 to 48 hours, depending on lab processing times. Your provider will discuss the findings with you during your follow-up visit.
What does a positive result mean?
A positive result indicates the presence of fungal DNA in your blood, strongly suggesting a fungal infection. Your doctor will work with you to determine the best course of treatment, which may include antifungal drugs.
Can I have this test if I’m not sick?
This test is primarily used in patients with symptoms or risk factors for fungal infections. If you’re healthy, it may not be necessary unless recommended by your provider for monitoring or research purposes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy