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Fungal respiratory pathogen detection by nucleic acid probe (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test checks for genetic material from certain fungi that may cause respiratory infections, using a probe to detect their presence in your blood.

Quick summary

Helps identify fungal infections in the lungs or bloodstream through genetic testing.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91085-1
Short code
Fungal 18s rRNA gene L. Resp Ql NAA+probe
Synonyms
Fungal 18s rRNA gene L. Resp Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects specific genetic sequences (nucleic acids) from fungi known to cause infections in the respiratory system. These sequences are analyzed using a molecular probe that binds to them with high specificity. This method is highly sensitive and can identify pathogens even at low concentrations in your blood sample.

How the Test Works

Your blood sample is processed to extract genetic material. The probe targets fungal DNA or RNA fragments unique to certain respiratory fungi. If the pathogen is present, the probe binds to its genetic material, triggering a detectable signal that confirms infection.

Why It’s Used

This test is particularly useful for diagnosing fungal infections in patients with weakened immune systems (e.g., due to cancer treatments, HIV, or organ transplants) or those with persistent lung symptoms that may suggest fungal causes.

Who Might Need This Test

Your healthcare provider may recommend this test if you have symptoms like persistent cough, fever, or breathing difficulties, especially if you’ve been exposed to fungi or have conditions increasing your risk of infection.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

How soon will I get results?
Results are typically available within 24 to 72 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
What does a positive result mean?
A positive result indicates the presence of fungal genetic material in your blood, suggesting a possible fungal respiratory infection. Further testing or medical evaluation will be needed to confirm the specific pathogen and guide treatment.
Can this test be used for other infections?
No, this test specifically targets fungal pathogens. It is not used for bacterial, viral, or other non-fungal infections.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy