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Fungal Antigen Detection (Quantitative) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of fungal antigens in your blood, which can help identify certain fungal infections.

Quick summary

["Helps diagnose fungal infections by detecting specific antigens in your bloodstream."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91091-9
Short code
Fungal ITS region Islt Ql NAA+probe
Synonyms
Fungal ITS region Islt Ql NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects fungal antigens—small molecules produced by fungi—that may be circulating in your blood if you have an active fungal infection. This can include infections caused by organisms like *Cryptococcus*, *Candida*, or others. The test is not specific to a single type of fungus but identifies general fungal presence.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like fever, fatigue, or organ dysfunction that could suggest a fungal infection, especially if you have a weakened immune system (e.g., from HIV, chemotherapy, or other conditions like diabetes). It may also be used in monitoring patients with known fungal exposure or risk factors.

How the Test Works

The test uses a sensitive immunoassay (likely a clia or fia method) to detect fungal antigens in a blood sample. The sample is typically drawn from a vein (venipuncture) and processed in a lab to measure antigen levels.

Sample Collection and Preparation

A blood sample is collected by a healthcare professional. You may feel a slight pinch when the needle is inserted, but the process is quick. The blood is then sent to a lab for testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test plays a key role in diagnosing fungal infections in patients who may not show obvious symptoms early on. High antigen levels can indicate an active infection, prompting further medical evaluation or treatment adjustments. It is particularly useful for identifying infections in immunocompromised individuals or those with chronic conditions that increase susceptibility.

Short name

Fungal Antigen Test

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of fungal antigens in your blood, which may indicate an active fungal infection. However, further testing or medical evaluation is needed to determine the specific type of fungus and guide treatment.
Can this test be used for routine check-ups?
No, this test is not typically used for routine check-ups. It is usually ordered when symptoms or risk factors suggest a fungal infection may be present.
How soon will I get results?
Results are usually available within 24 to 48 hours, depending on your lab’s processing schedule. Your healthcare provider will discuss the results with you during your follow-up visit.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy