Skip to content

Mycobacterium tuberculosis and other mycobacterial blood culture (aerobic and anaerobic)

Published: August 9, 2026Updated: August 16, 2026

This test checks for the presence of bacteria from the *Mycobacterium* genus, including *Mycobacterium tuberculosis* (the cause of tuberculosis), in your blood. It involves growing samples of your blood in special media to detect any bacterial growth over time.

Quick summary

["Helps identify infections that may require targeted antibiotics or further testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
97758-7
Short code
Fung+Mycobact sp Bld Cult
Synonyms
Fung+Mycobact sp Bld Cult
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like fever, chills, night sweats, unexplained weight loss, or fatigue—especially if you’ve been exposed to tuberculosis or have a weakened immune system. It’s also used in people with chronic illnesses (like HIV) or those who’ve recently traveled to areas with higher tuberculosis rates.

How the Test Works

A small sample of your blood is drawn and placed in sterile containers with nutrient media. These containers are incubated in special conditions to allow any mycobacteria to grow over several days to weeks. If bacteria are present, they’ll multiply and can be identified later through additional testing.

What to Expect Before the Test

No special preparation is needed, but inform your provider if you’re on blood-thinning medications or have a history of bleeding disorders. Avoid alcohol before the draw if your provider advises it.

What to Expect During the Test

You’ll have a needle inserted into a vein (usually in your arm), and blood will be drawn into a syringe or collection tube. It may feel like a small pinch, but it shouldn’t cause significant discomfort. The process takes about 5 minutes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate an active mycobacterial infection, which may require treatment with antibiotics (often a combination) to kill the bacteria. Negative results mean no detectable mycobacteria were found in your blood sample at the time of testing, but infections can sometimes be missed if the sample isn’t taken early or if the bacteria are present in low numbers. Follow-up testing or cultures may be needed if symptoms persist.

Short name

Mycobacterial Blood Culture

Frequently asked questions

How long does it take to get results?
Results can take several days to weeks, depending on the growth of bacteria. Some labs may provide preliminary findings sooner, but final identification of the bacteria often requires additional testing (like PCR or culture confirmation).
What if I have a negative result but still feel sick?
A negative blood culture doesn’t rule out tuberculosis or other mycobacterial infections. If you continue to have symptoms, your provider may order additional tests (like a sputum culture, chest X-ray, or PCR test) to investigate further.
Can I take antibiotics before the test?
Yes, but inform your healthcare provider immediately if you start antibiotics before or after the blood draw. Antibiotics can interfere with the test results and may affect the accuracy of detecting the bacteria.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy