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Fungal Nucleic Acid Detection by Probe (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test detects genetic material from certain fungi in your blood, helping doctors check for infections caused by fungi like Candida or Cryptococcus.

Quick summary

["This test helps identify fungal infections early, which is important for starting the right treatment quickly."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98398-1
Short code
Fungus Islt NAA+probe
Synonyms
Fungus Islt NAA+probe
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test looks for specific genetic sequences (nucleic acids) from fungi in your blood. These sequences are unique to certain types of fungi and can indicate an active infection. The probe method amplifies and detects these sequences to confirm presence.

Why It’s Done

Doctors may order this test if you have symptoms like fever, fatigue, or organ dysfunction that could suggest a fungal infection, especially in high-risk groups such as people with weakened immune systems (e.g., from HIV/AIDS, chemotherapy, or organ transplants).

How It Works

A small blood sample is taken and analyzed using a specialized probe technique. This method detects fungal genetic material without needing to grow the fungus in a lab first, making it faster and more sensitive for certain infections.

Who Might Need This Test

This test is typically recommended for individuals at higher risk of fungal infections, such as those with immune system disorders, recent surgeries, or prolonged use of broad-spectrum antibiotics.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results indicate the presence of fungal genetic material, suggesting a fungal infection that may require antifungal treatment. Negative results mean no detectable fungal genetic material in the sample, but further testing or monitoring may still be needed depending on clinical symptoms and risk factors.

Short name

Fungal Probe Test

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of fungal genetic material in your blood, which could indicate an active fungal infection. This finding will guide your healthcare provider in determining the best treatment plan, which may include antifungal medications.
What if my test is negative?
A negative result means no detectable fungal genetic material in your sample. However, this does not definitively rule out a fungal infection. Your doctor may recommend additional tests, closer monitoring, or further evaluation based on your symptoms and risk factors.
How soon will I get results?
Results are typically available within a few days to a week, depending on lab processing times. Your healthcare provider will discuss the results with you in detail.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy