Genetic Mutation Analysis for Fusion Gene Detection (Blood)
This test checks for specific genetic changes (mutations) in blood that may form when two different genes join together, often linked to certain cancers or blood disorders.
["Some cancers, like certain leukemias or lymphomas, may involve unusual gene fusions that can help guide treatment decisions."]
Key facts at a glance
- LOINC
- 77634-4
- Short code
- FUS gene Mut Anl Bld/T
- Synonyms
- FUS gene Mut Anl Bld/T
- Category
- chemistry
- Sample
- whole-blood
- Container
- Lavender-top (EDTA)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 3 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test looks for the presence of fusion genes created by rearrangements in your DNA. These rearrangements can occur when parts of two different genes accidentally swap places, forming a new gene that may drive abnormal cell growth.
How the Test Works
Blood is drawn and analyzed using advanced genetic testing methods to detect the fusion gene sequences. This may involve techniques like next-generation sequencing or polymerase chain reaction (PCR) to identify the specific genetic changes.
Why It Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms or a history suggestive of a blood-related cancer (e.g., acute myeloid leukemia, chronic myeloid leukemia, or other hematologic malignancies) or if you are at higher risk due to genetic factors.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast or avoid certain medications before the blood draw. Your provider will explain any specific instructions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Detecting fusion genes can help confirm a diagnosis, determine the type of cancer, and guide personalized treatment plans. Some fusion genes are associated with specific responses to targeted therapies, which may improve outcomes.
Short name
Fusion Gene Mutation Test (Blood)
Frequently asked questions
What does a positive result mean?
Will this test affect my treatment?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy