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C-reactive protein (CRP) with high-sensitivity measurement (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures a protein called C-reactive protein, which your body produces in response to inflammation. It’s often used to check for signs of inflammation or infection.

Quick summary

["hs-CRP helps track inflammation, aiding early detection of conditions like heart disease or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
77726-8
Short code
FVIII+vWf:RCo Gvn Dose FVIII dose-aCnc
Synonyms
FVIII+vWf:RCo Gvn Dose FVIII dose-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
fviii-dosing
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why hs-CRP Matters in Your Health

High-sensitivity CRP (hs-CRP) is a blood test that detects very small amounts of a protein called C-reactive protein. This protein rises when your body is fighting inflammation, which can occur with infections, injuries, or certain diseases like arthritis or heart disease. Unlike standard CRP tests, hs-CRP can pick up even slight increases, helping doctors monitor risk more precisely.

What Does hs-CRP Test for?

hs-CRP is primarily used to assess inflammation levels. It can help identify people at higher risk for conditions like cardiovascular disease, where inflammation plays a role. Some doctors also use it to monitor treatment progress in chronic inflammatory conditions.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is sent to a lab where it’s analyzed to measure hs-CRP levels. Results are typically ready within a few days.

What Are Possible Results?

Results are reported in milligrams per liter (mg/L). A low or normal level suggests little to no inflammation, while higher levels may indicate ongoing inflammation or risk factors for certain health issues.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: hs-CRP and Health Risks

Short name

hs-CRP

Frequently asked questions

What does an elevated hs-CRP level mean?
An elevated hs-CRP level may signal inflammation in your body, which can be linked to conditions like heart disease, arthritis, or infections. However, it’s not a definitive diagnosis—your doctor will consider other factors, such as symptoms and medical history, to interpret results.
Can hs-CRP be used to prevent heart disease?
hs-CRP is sometimes used as a marker to help assess cardiovascular risk. While it can’t prevent disease on its own, it may guide lifestyle or treatment recommendations to reduce inflammation and lower risk.
How often should I get an hs-CRP test?
Your doctor will determine how often you need this test based on your health status, risk factors, and medical needs. For example, people with heart disease or autoimmune conditions may get it more frequently than others.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy