Genetic test for FGFR3 gene mutations (serum/plasma)
This test checks for changes (mutations) in the FGFR3 gene, which may be linked to certain cancers or inherited conditions.
["Helps identify genetic variations that could influence cancer risk or treatment options."]
Key facts at a glance
- LOINC
- 75392-1
- Short code
- FXN gene GAA Rpt Amn/CVS Ql
- Synonyms
- FXN gene GAA Rpt Amn/CVS Ql
- Category
- chemistry
- Sample
- fluid
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 2-5 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h
- Hemolysis max
- 300
- TAT
- 4–24 hours
- Order
- routine
What Is This Test For?
The FGFR3 gene provides instructions for making a protein that plays a role in cell growth and development. Mutations in this gene can sometimes lead to overactive cell growth, which may contribute to certain types of cancer, such as certain types of bone or soft tissue sarcomas. This test is often used in research or specialized clinical settings to assess genetic risk or guide treatment decisions for specific conditions.
How Is the Sample Collected?
A blood sample (serum or plasma) is typically collected from a vein in your arm. This is a standard procedure where a healthcare provider will clean the area, insert a small needle, and draw blood into a tube. You may feel a slight pinch, but it usually doesn’t cause significant discomfort.
What Does the Test Result Mean?
Results can vary widely depending on the specific mutation detected and clinical context. Some mutations may increase cancer risk, while others may be associated with inherited conditions like certain bone disorders. Your healthcare provider will discuss the results in detail based on your medical history and symptoms.
When Might I Need This Test?
This test may be recommended if you have a family history of certain cancers, symptoms suggestive of a genetic condition, or if you are part of a clinical study investigating genetic mutations related to FGFR3.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Genetic testing for FGFR3 mutations can play a role in cancer diagnosis, risk assessment, and personalized treatment planning. Mutations may influence how certain cancers respond to targeted therapies, so results can help guide treatment options tailored to your genetic profile.
Short name
FGFR3 Mutation Analysis
Frequently asked questions
Why was this test ordered?
What does a positive result mean?
Do I need to prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy