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Serum or Plasma Total Protein Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein in your blood, which includes both albumin and globulin proteins.

Quick summary

["Total protein helps assess your body’s protein balance and overall kidney function."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
53864-5
Short code
GAA Mut Anl Bld/T
Synonyms
GAA Mut Anl Bld/T
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why It’s Done

Your doctor may order a total protein test to check for conditions like kidney disease, liver problems, malnutrition, or certain infections. It can also help diagnose conditions such as multiple myeloma or autoimmune disorders.

What to Expect

A small blood sample is taken from a vein, usually in your arm. You may feel a slight pinch, but it shouldn’t cause significant discomfort. The test is quick and doesn’t require special preparation.

Normal vs. Abnormal Results

While reference ranges vary by lab, higher than expected protein levels might suggest conditions like dehydration or certain cancers, while lower levels could indicate malnutrition, liver disease, or kidney problems.

Common Conditions Linked to Results

Elevated protein levels may be seen in chronic kidney disease, multiple myeloma, or severe dehydration. Low protein levels can signal liver disease, malnutrition, or conditions affecting protein synthesis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Total Protein

Frequently asked questions

How long does it take to get my results back?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Follow-up with your healthcare provider if you have any questions or concerns about your results.
Can I eat or drink anything before this test?
No special preparation is needed for this test. You can eat, drink, and go about your normal activities as usual. However, always follow any specific instructions your doctor provides.
What does it mean if my protein levels are too high?
High protein levels may suggest conditions like dehydration, kidney disease, or certain cancers. Your doctor will discuss your results and any further tests needed to understand the cause.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy