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Gamma-aminobutyric acid (GABA) in serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of gamma-aminobutyric acid, a key neurotransmitter in your brain that helps regulate nerve cell activity.

Quick summary

["GABA levels can help assess brain chemistry and may be checked for neurological conditions or symptoms like anxiety or seizures."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
26861-5
Short code
GABA Amn-sCnc
Synonyms
GABA Amn-sCnc
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms such as anxiety, seizures, sleep disorders, or neurological concerns. It could also be part of a broader evaluation for conditions like epilepsy, brain injuries, or certain metabolic disorders.

What to Expect Before the Test

No special preparation is typically needed. You may have a small needle inserted into a vein in your arm, and a small amount of blood will be drawn. If you’re concerned about blood draws, let your provider know.

What the Results Mean

GABA levels can vary based on health, medications, and other factors. While abnormal results may suggest neurological issues, they don’t always indicate a specific condition without further evaluation. Your provider will discuss the results with you.

Common Reasons for Testing

This test is often used to monitor GABA levels in cases of suspected neurotransmitter imbalances, epilepsy, or other neurological disorders. It may also be part of research or specialized diagnostic processes.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

GABA Level

Frequently asked questions

How does GABA relate to my health?
GABA is a natural chemical in your brain that helps calm nerve activity. Low levels may be linked to conditions like anxiety, seizures, or certain neurological disorders, while high levels could indicate metabolic or genetic factors. Your provider will interpret results in the context of your symptoms and medical history.
What does a low or high GABA level indicate?
Abnormal GABA levels alone don’t diagnose a condition. They may signal a need for further testing or evaluation, such as imaging, genetic testing, or additional neurological assessments. Always discuss results with your healthcare team.
Can medications affect GABA levels?
Yes, certain medications—like antiepileptics, antidepressants, or some psychiatric drugs—can influence GABA levels. If you’re on medication, mention it to your provider before or after the test to ensure accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy