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Gamma-Aminobutyric Acid (GABA) in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of gamma-aminobutyric acid, a key neurotransmitter in your brain and spinal cord, found in cerebrospinal fluid.

Quick summary

["GABA helps regulate brain activity and may be checked if you have neurological concerns."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
103715-9
Short code
GABAAR IgG CSF Ql CBA IFA
Synonyms
GABAAR IgG CSF Ql CBA IFA
Category
coagulation
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cba-ifa
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like seizures, headaches, movement disorders, or neurological conditions. It could also be part of a broader evaluation for conditions affecting brain chemistry, such as epilepsy, brain tumors, or metabolic disorders.

What to Expect Before the Test

No special preparation is needed for this test. You’ll have a small needle inserted into your back to collect a sample of cerebrospinal fluid, usually done in a hospital or clinic setting. The procedure is quick but may cause mild discomfort.

What the Test Results Mean

Abnormal levels of GABA in CSF might indicate issues like brain tumors, epilepsy, or other neurological disorders. Your results will be interpreted by a healthcare professional based on your symptoms and medical history.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions such as epilepsy, certain brain tumors, or metabolic disorders that affect neurotransmitter balance.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

GABA CSF

Frequently asked questions

What does my GABA CSF test result indicate?
Your results will be reviewed by a specialist who considers your symptoms, medical history, and other test findings. Low or high GABA levels may suggest specific neurological conditions that require further evaluation, such as genetic disorders or brain abnormalities.
How often will I need this test?
The frequency depends on your diagnosis and treatment plan. If you have a known condition like epilepsy or a brain tumor, your doctor may order this test periodically to monitor changes in your condition.
Can I eat or drink before this test?
No special diet or restrictions apply. You can eat and drink normally before the test, as it involves collecting CSF through a spinal tap.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy