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GABA (Gamma-Aminobutyric Acid) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of GABA, a natural chemical in your body that helps regulate brain activity, in your blood.

Quick summary

["GABA is involved in calming nerve signals and may be checked if you have neurological concerns or certain conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
101875-3
Short code
GABAAR IgG Titr Ser CBA IFA
Synonyms
GABAAR IgG Titr Ser CBA IFA
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
8
Ref high
61
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cba-ifa
CPT
82977
SNOMED
3110003
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

GABA (Gamma-Aminobutyric Acid) is a neurotransmitter that plays a key role in reducing brain activity. Your body produces it naturally, and small amounts can be found in your blood. This test helps assess its concentration, which may be relevant in certain neurological or psychiatric evaluations.

Why Might You Need This Test?

A GABA test may be ordered if you have symptoms like seizures, anxiety, or sleep disorders. Doctors might also check it in people with epilepsy, autism spectrum disorder, or other neurological conditions where GABA levels could be important.

Sample Collection and Preparation

A blood sample is taken from a vein in your arm. You may feel a small pinch when the needle is inserted, but the process is quick. The sample is then sent to a lab for analysis. No special preparation is needed, but avoid eating or drinking for a few hours before the test if instructed.

What Are Possible Results?

Results are typically reported as a concentration level of GABA in the blood. While reference ranges can vary by lab, they generally reflect normal physiological levels. Abnormal results may suggest conditions affecting GABA production or function.

Reference range

Adult males: 8-61 U/L; Adult females: 5-36 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

GABA Level

Frequently asked questions

What Does a High or Low GABA Level Mean?
Elevated GABA levels might be seen in certain neurological disorders or after exposure to GABA-enhancing medications. Low levels could be linked to conditions affecting GABA synthesis or receptor function, such as some forms of epilepsy or certain psychiatric conditions. Always discuss results with your healthcare provider.
How Often Should I Get This Test?
This test is usually not routine unless recommended by your doctor for specific symptoms or conditions. Follow your healthcare provider’s guidance on how often to repeat it.
What Can Affect My Results?
Certain medications, such as anticonvulsants or anxiolytics, may influence GABA levels. Stress, diet, or recent alcohol consumption could also impact results. Always inform your doctor about all medications or supplements you take.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy