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Gamma-Glutamyl Transferase (GGT) in Cerebrospinal Fluid (CSF)

Published: August 9, 2026Updated: August 16, 2026

This test measures the enzyme GGT in your cerebrospinal fluid, which may help assess liver function or detect certain neurological conditions.

Quick summary

["GGT in CSF can signal liver issues or brain/nerve problems, though results are interpreted with other tests."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
109475-4
Short code
GABABR IgG Msmt CSF
Synonyms
GABABR IgG Msmt CSF
Category
coagulation
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like headaches, neurological issues, or if you’re being evaluated for conditions like meningitis, brain tumors, or liver disease. It’s sometimes used alongside other tests to better understand your health status.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your back to collect a small amount of CSF, usually done in a hospital or clinic setting. You may feel mild pressure or discomfort, but it’s generally quick and painless.

What the Results Mean

Elevated GGT in CSF can sometimes indicate inflammation, infection, or structural changes in the brain or spinal cord. However, results alone aren’t diagnostic—your doctor will review them with your full medical history and other test results.

Common Conditions Linked to Abnormal Results

While GGT in CSF isn’t as commonly elevated as in blood tests, high levels may be associated with conditions like meningitis, brain tumors, or certain neurological disorders. Low levels are less commonly reported but may warrant further investigation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

CSF GGT

Frequently asked questions

What does a high GGT level in CSF usually mean?
A high GGT level in CSF can suggest inflammation, infection, or other abnormalities in the brain or spinal fluid, but it’s not definitive on its own. Your doctor will consider your symptoms, other test results, and medical history to interpret the findings.
Can I eat or drink before this test?
No special diet or restrictions apply. You can eat and drink normally before the procedure, as it’s not affected by food or hydration.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab’s processing time. Your doctor will contact you with the final report once it’s ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy