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Gamma-Glutamyl Transferase (GGT) in Serum/Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the activity of an enzyme called gamma-glutamyl transferase, which helps assess liver health and detect potential liver damage or disease.

Quick summary

["GGT can indicate liver problems or exposure to certain medications/toxins."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
93428-1
Short code
GABABR IgG SerPl Ql CBA IFA
Synonyms
GABABR IgG SerPl Ql CBA IFA
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
cba-ifa
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Gamma-Glutamyl Transferase (GGT) Used For?

GGT is primarily used to evaluate liver function and identify conditions such as alcohol-related liver disease, hepatitis, bile duct obstructions, or certain medications that may affect the liver. It can also help monitor liver health in people with known liver issues or those taking drugs that require liver metabolism.

How Is GGT Tested?

A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab where the enzyme activity is measured using a specialized test.

Why Might My GGT Levels Be High?

Elevated GGT levels may suggest liver damage, chronic alcohol use, certain medications, or conditions like fatty liver disease. However, other factors such as heart disease, kidney problems, or smoking can also influence GGT levels.

What Are Common Causes of Low GGT Levels?

Low GGT levels are less common but may occur in people with certain genetic conditions, liver diseases like cirrhosis, or in cases where the liver is not functioning properly due to other health conditions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

GGT

Frequently asked questions

Why was my GGT test ordered?
Your doctor may have ordered a GGT test to check for liver problems, monitor a known liver condition, or investigate symptoms like fatigue, abdominal pain, or jaundice. It can also be used alongside other tests to diagnose or guide treatment for conditions affecting the liver.
How often should I get a GGT test?
The frequency of GGT testing depends on your health status. If you have no known liver issues, your doctor may recommend it only if you have risk factors (like heavy alcohol use) or symptoms. If you have liver disease, your doctor will likely schedule follow-up tests based on your treatment plan.
Can lifestyle changes affect GGT levels?
Yes, lifestyle factors such as alcohol consumption, diet, and smoking can impact GGT levels. Reducing alcohol intake, eating a balanced diet, and avoiding smoking may help lower GGT levels and support liver health.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy